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Compound InformationSONAR Target prediction
Name:

R(-)-2,10,11-Trihydroxyaporphine hybrobromide

Unique Identifier:LOPAC 00266
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:BrC17H18NO3
Molecular Weight:347.099 g/mol
X log p:8.916  (online calculus)
Lipinksi Failures1
TPSA3.24
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:0
Canonical Smiles:Br.CN1CCc2cc(O)cc3c2C1Cc1ccc(O)c(O)c13
Class:Dopamine
Action:Agonist
Selectivity:DRD2

Found: 9 active | as graph: single | with analogs 1 2 3 4 5 6 7 8 9 Next >> 
Species: 4932
Condition: CIN2
Replicates: 2
Raw OD Value: r im 0.7299±0.062579
Normalized OD Score: sc h 0.8762±0.0787248
Z-Score: -9.1323±5.06439
p-Value: 0.0000000141847
Z-Factor: -1.35908
Fitness Defect: 18.0711
Bioactivity Statement: Active
Experimental Conditions
Library:Lopac
Plate Number and Position:6|E6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.90 Celcius
Date:2005-12-07 YYYY-MM-DD
Plate CH Control (+):0.0395±0.00186
Plate DMSO Control (-):0.82±0.01296
Plate Z-Factor:0.9279
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DBLink | Rows returned: 2
5020
6603797

internal high similarity DBLink | Rows returned: 6
LOPAC 00270 0.9018
LOPAC 00257 0.9187
LOPAC 00265 0.9187
LOPAC 00267 0.9375
LOPAC 01342 0.9800
SPE01500129 0.9803

active | Cluster 1444 | Additional Members: 3 | Rows returned: 2
LOPAC 00265 0.358208955223881
LOPAC 00267 0

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